BCG & SCID screening:
What you need to know

07.12.2023 Category: General Health Author: Anna Chapman & Lucy Mildren

In September 2021, Public Health England released new rules surrounding the timing of BCG vaccination, increasing the minimum age of vaccination to 28 days. This has been implemented in line with a pilot disease screening programme that tests eligible newborns for Severe Combined Immunodeficiency (SCID), the outcome of which becomes available by the time the baby is 6 weeks old. It is important that we wait for the result of this test before giving the BCG vaccine.

What is SCID screening?
All newborn babies in the UK are currently offered blood spot screening (heel prick test) that looks for 9 rare diseases, including sickle cell and cystic fibrosis. The NHS is considering introducing an additional test for Severe Immunodeficiency (SCID), a name given to a group of rare, inherited disorders that cause major abnormalities in the immune system. Affected infants have an increased risk of life-threatening infections and will normally become severely unwell in the first few months of life. Without treatment they will rarely live past their first birthday. About 14 babies a year are born in England with SCID.

The evaluation of this testing, which began on 6th September 2021, is taking place in 6 areas across England and will cover around 60% of new born babies. It is running alongside the existing blood spot screening and the intention is to roll it out nationally once the 2 year evaluation has been made. 

Why does this affect the BCG vaccination?
Bacillus Calmette-Guérin (BCG) is a live attenuated vaccine that can cause problems if given to an immunocompromised person. Treatment for SCID is more complicated if the child has received the BCG vaccine, so it is important that if your child has been tested. We wait for a negative result before vaccinating. 

What we need from you:
If your child was included in the SCID programme, you will need to provide a letter that confirms the negative result of screening.

If your child was born outside of the programme areas and therefore, not included in the SCID programme, we will need to see a letter confirming this. 

In either case, please bring the letter with you to your appointment, as well as your child’s vaccination book.

Nb. If your child was born before 1st September 2021, before the programme was introduced, no letter will be needed. 

 

For more information on:

BCG vaccination

Other Childhood Vaccinations

Urgent Polio Boosters - Statement

11.08.2022 Category: General Health Author: Anna Chapman

Urgent polio boosters advised for London children

UK Health Security Agency (UKHSA) has announced that all children aged 1-9 years regardless of previous immunisation status are recommended a polio vaccine booster from all London boroughs.

The virus, which can cause paralysis, has been found 116 times in London’s waste water between February and July this year. 

In the UK, the overall risk of paralytic polio is considered low because most people are protected from this by vaccination. However, due to the recent discovery of type 2 vaccine-derived poliovirus in sewage in multiple locations in London, the Joint Committee on Vaccination and Immunisation (JCVI)  have advised that booster vaccinations in all children aged 1-9 years is an appropriate course of action.

The UKHSA says most of the samples detected are the safe vaccine form of polio, but “a few” have mutated enough to be considered dangerous.

Parents should seek the polio vaccine booster as soon as possible – even if their child is up-to-date with their childhood vaccinations. 

The aim is two-fold; to ensure a high level of protection from polio paralysis and help reduce further spread of the polio virus across London and beyond.

Booster Polio Vaccinations at Fleet Street Clinic

We offer two vaccinations in-clinic that offer protection from Polio:

Revaxis Vaccine: Suitable for children from 6 years and above
Protects against:  Diphtheria, Tetanus, Polio
Cost: £47 + £20 appointment fee
Call to book

Repevax Vaccine: Suitable for children from 3 years and above
Protects against: Diphtheria, Tetanus, Polio & Whooping Cough
Cost: £69 + £20 appointment fee
Call to book

Both of these vaccinations are inactivated, and given by injection. They are both licensed as booster doses, and are not intended for primary immunisation.

More information on the Polio vaccines available at Fleet Street Clinic, click here.


Primary Polio Vaccination
Unfortunately, we do not offer the infant/ baby vaccination for Polio – in the UK this would be the Infanrix-Hexa, the 6-in-1 vaccine. We have no suitable vaccination for children under the age of 3, or for those requiring their primary immunisation against Polio. 

Please contact your NHS doctor or an alternative provider to see if they can help you further.

Dr Vanessa Saliba, Consultant Epidemiologist at UKHSA, said:

“It is vital parents ensure their children are fully vaccinated for their age. Following JCVI advice all children aged 1 to 9 years in London need to have a dose of polio vaccine now – whether it’s an extra booster dose or just to catch up with their routine vaccinations. It will ensure a high level of protection from paralysis. This may also help stop the virus spreading further.”

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More information on Polio and the emerging London findings:

What is Polio?
Polio is a serious viral infection that is transmitted through the stool’s of an infected person through contaminated water, food or surfaces. It can cause unpleasant flu-like symptoms and in severe cases, cause paralysis.

What are the symptoms of Polio?
The majority of people with the infection have no symptoms but some feel as if they have the flu, with:

  • high temperature
  • sore throat
  • headache
  • abdominal pain
  • sickness

In severe cases of polio, the virus can attack the nerves in the spine and brain which can cause paralysis. In some cases, it can cause persistent or lifelong difficulties and even be life-threatening.

Where has Polio been found?
According to the UKHSA statement, in addition to the findings earlier this year of type 2 poliovirus (PV2) collected from the Beckton sewage treatment works, further upstream sampling undertaken by the UK Health Security Agency (UKHSA) and the Medicines and Healthcare products Regulatory Agency (MHRA) has now identified at least one positive sample of the poliovirus, currently present in parts of the following boroughs:

  • Barnet
  • Brent
  • Camden
  • Enfield
  • Hackney
  • Haringey
  • Islington
  • Waltham Forest

The sampling has also detected the virus in lower concentrations and frequency in areas adjacent to the Beckton catchment area to the South (immediately below the Thames) and to the east of Beckton. However, it is not clear whether the virus has established itself in these areas or if the detections are due to people from the affected area visiting these neighbouring areas.

How many cases of Polio have been identified?
To date, again based on the UKHSA statement, ‘a total of 116 PV2 isolates have been identified in 19 sewage samples collected in London between 8 February and 5 July this year’.

A further 15 sites in London will start sewage sampling in mid-August, and 10 to 15 sites will be stood up nationally to determine if poliovirus is spreading outside of London.

 

To book your child’s Polio Booster Vaccination, call +44 20 7353 5678 today.

Travel Advice: Measles Outbreaks Continue in Europe

28.05.2019 Category: Travel Health Author: Anna Chapman

Parents are being urged to get their children vaccinated for measles, mumps and rubella following outbreaks of measles across Europe:

Anyone who is eligible to get vaccinated should get the MMR vaccine.

A measles outbreak across Europe has left UK officials urging parents to get their children vaccinated for measles, mumps and rubella.  As measles is highly infectious, anyone who has not received 2 doses of the MMR vaccine is at risk. Particularly those unvaccinated people travelling to countries where there are currently large outbreaks of measles.

In the first three months of this year, there have been 231 confirmed cases of measles and 795 of mumps. While Public Health England (PHE) figures showed while measles cases were lower than the 265 reported during the same period last year, they had more than doubled compared to the 97 reported between October and December. The number of mumps cases has nearly tripled compared to the 275 cases during the first three months of 2018. No new cases of rubella have been reported.

PHE has now appealed to parents to make sure their children receive the MMR vaccine when it’s offered, or to get a GP appointment booked if they missed it. Officials have also warned that not only is measles highly contagious, but it can also kill a child if they are not vaccinated. Anyone who has not received two doses of MMR vaccine is at risk of measles as it is highly contagious.

There have been 3,789 cases of measles in Europe during the first three months of this year, according to the European Centre for Disease Prevention and Control. The highest numbers were in Romania, France, Poland and Lithuania.

Advice for travellers

For all those planning to travel to Europe, make sure you are up-to-date with all currently recommended UK vaccines. This includes two doses of the MMR vaccine for protection against measles, mumps and rubella.

Anyone who is not sure if they are protected should check with their GP practice. Vaccination is usually done within your childhood vaccinations. However, the MMR vaccine is available to all adults and children who have not had their two-dose course. In some cases, the MMR vaccine can be offered to babies from six months of age. Cases such as travelling to countries where measles is common, or during an outbreak situation. Book a travel consultation with our travel nurse for advice on the best option for your children before you travel.

Head of immunisation at PHE, Dr Mary Ramsay, warned with measles outbreaks across parts of Europe, families should make sure they are vaccinated before travelling. ‘There are measles outbreaks happening across Europe so if you are planning to travel, make sure you check with your GP and catch-up if needed.’

Herd immunity

Measles elimination can only be sustained by maintaining and improving coverage of MMR vaccine in children, and by using all opportunities to catch up older children and adults who missed getting the MMR vaccine.

To achieve herd immunity for measles at least 90 to 95 per cent of the population needs to be fully protected. PHE said 94.9 per cent of eligible children aged five received their first dose of MMR in quarter 4 of 2018. However, the second dose of protection falls to 87.4 per cent for children aged five.

Fleet Street Clinic’s medical director, Dr Richard Dawood explains, ‘When the rate of vaccination in the general population falls below 95%, outbreaks occur and can easily spread, with the highest impact on those most vulnerable populations, undermining years of hard work around the world to bring measles under control.’

Vaccination against Measles, Mumps & Rubella

One dose of the MMR vaccine is about 90 to 95 per cent effective at preventing measles. Protection rises to around 99 per cent after the second dose. Two doses of MMR in a lifetime are needed for a person to be considered fully protected.

The MMR vaccine schedule:

  • Two doses, to be given at least 4 weeks apart.
  • If the first dose is given before 12 months of age (due to the need for early protection), this should be discounted and the child should continue to receive 2 doses as per the normal schedule.
  • The vaccine is also available to all adults and children who are not up-to-date with their 2 doses.

Anyone who is not sure if they are fully vaccinated should check with their GP.

You can book all vaccination appointments online.

Meningitis vaccines available

19.05.2017 Category: News Author: Anna Chapman

Recent media reports have raised awareness of the effects of Meningitis B and the importance of the meningitis vaccine (if your child is aged under 12 months, the vaccine still readily available via your NHS doctor). Less well-known is the fact that there are different strains of Meningitis, with different vaccines protecting against them. Some of the recent cases reported in the media have actually been caused by Meningitis W or Meningitis C rather than the B strain, and it is important to know that vaccine protection is still widely available against those strains.

Strains and Meningitis Vaccines:

  • Meningitis B: the protective single-strain meningitis B vaccine is Bexsero
  • Meningitis A C W Y: the 4-strain vaccines Menveo and Nimenrix offer protection.

Meningococcal Meningitis and its Symptoms

Meningococcal meningitis is a bacterial infection that causes inflammation of the protective membranes surrounding the brain and spinal cord. It can affect people of any age, but those most commonly affected are children under 5, and  teenagers and young adults heading off to university.

Initial symptoms may be similar to flu, progressing to:

  • A high temperature/fever, with cold hands and feet
  • Vomiting
  • Refusal to eat
  • Drowsiness
  • Floppy and unresponsive
  • Rapid breathing
  • Neck stiffness
  • Bright light sensitivity
  • Pale, blotchy skin, and a red rash that doesn’t fade when a glass is rolled over it
  • Convulsions or seizures

Further information: https://www.meningitisnow.org/meningitis-explained/

The specialists at the Fleet Street Clinic recommend getting your children vaccinated not just against Meningitis B, but against Meningitis A,C,W & Y strains as well (the vaccine is currently available and in stock).

Meningitis B Vaccines Availability

We currently do have a limited supply of Meningitis B vaccine, available on a first come, first served basis. You can book a Meningitis B vaccination appointment online